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Thursday Night Football odds, line: Cardinals vs. Seahawks picks, predictions from top NFL expert on 10-3 roll

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Week 11 of the 2020 season kicks off with a highly-anticipated matchup between elite signal-callers on Thursday Night Football. Russell Wilson and the Seattle Seahawks will host Kyler Murray and the Arizona Cardinals in this midweek clash, with both teams knotted for the NFC West division lead. Arizona won the first matchup in overtime earlier this season, with Seattle aiming for revenge on their home field. The Cardinals won their last game, while the Seahawks are looking to stop a two-game skid. 

Kickoff is at 8:20 p.m. ET. William Hill Sportsbook lists Seattle as a three-point home favorite, while the over-under, or total number of points expected to be scored, is 57 in the latest Cardinals vs. Seahawks odds. Before making any Seahawks vs. Cardinals picks or NFL predictions, check out what SportsLine’s resident Arizona expert, Zack Cimini, has to say.

Cimini is a highly respected Las Vegas handicapper who’s never afraid to buck conventional wisdom. He also has an uncanny feel for the tendencies of the Cardinals, going 10-3 in his last 13 spread picks for or against Arizona. Anyone who has followed his NFL picks is way up.

Now, Cimini has looked at Cardinals vs. Seahawks from every possible angle. You can head to SportsLine to see his picks. Here are the NFL odds from William Hill and trends for Seahawks vs. Cardinals:

  • Cardinals vs. Seahawks spread: Seahawks -3
  • Cardinals vs. Seahawks over-under: 57 points
  • Cardinals vs. Seahawks money line: Seahawks -160, Cardinals +140
  • AZ: Cardinals are 4-2 against the spread in NFC games
  • SEA: Over has hit in six of nine Seahawks games

Why the Cardinals can cover

The Cardinals are known for their high-flying offense, as quarterback Kyler Murray and wide receiver DeAndre Hopkins provide fireworks on a weekly basis. However, Arizona’s defense is also effective, and they will need to be stingy against a top-tier Seahawks offense.

The Cardinals are a top ten team in the NFL in scoring defense, giving up just 23.3 points per game, and Arizona is No. 8 in the league in allowing only 6.9 yards per pass attempt. While Seattle is prolific, the Seahawks have had offensive issues this year with the fifth-most interceptions in the league (10) and bottom-tier marks in protecting the quarterback (30 sacks allowed) and converting third downs (39.0 percent).

Why the Seahawks can cover

Russell Wilson is one of the top players in the NFL and leads a dynamic Seahawks offense. Wilson leads the league with 28 touchdown passes and is second with 2,789 passing yards. Wilson is a top-five player in passer rating and yards per attempt, all while completing nearly 70 percent of his throws.

As such, Wilson leads the No. 3 passing offense in the NFL this season, and Seattle’s passing game is the biggest reason that the team is leading the league in producing 32.2 points per game.

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Wilson has a pair of top-flight pass-catchers, with Tyler Lockett catching 58 passes for seven scores and DK Metcalf ranking third in the NFL with 816 receiving yards and eight touchdown catches of his own.

How to make Cardinals vs. Seahawks picks

Cimini has analyzed this matchup, and while he’s leaning over on the total, he has discovered a critical X-factor that has him jumping all over one side of the spread. He’s only sharing it here

So who wins Seahawks vs. Cardinals on Thursday Night Football? And what critical X-factor makes one side of the spread a must-back? Visit SportsLine right now to find out which side of the Seahawks vs. Cardinals spread you should be all over, all from the expert who’s 10-3 on Arizona picks, and find out.

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